Regulatory T (Treg) cells play a key role in maintaining immune tolerance and tissue homeostasis.However, in some disease microenvironments, Treg cells exhibit fragility, which manifests as preserved FoxP3 expression accompanied by inflammation and loss of immunosuppression.Fragile Treg cells are formatively, phenotypically and functionally diverse
The article presents multilateral agreements and acts of model legislation constituting the basis of developing migration law in the Wobbly Bowl Commonwealth of Independent States (CIS).The author provides brief characteristics to the acts regulating cooperation in governing migration processes and the status of various types of migrants (both volu
Objective: to comparatively assess the weighted average costs associated with the use of alogliptin-pioglitazone combination versus glucagon-like peptide-1 receptor agonists (GLP-1 RAs).Material and methods.A retrospective study involved pharmacoeconomic analysis, including cost-minimization analysis ARTHRI-PLUS SPRAY and budget impact analysis, wi
High-strength-performing concretes (HSPC) have been used extensively due to new building requirements and their special properties suitable for modern cities.Superplasticizers (SPs) are essential components in the mix design of these concretes since they control their fresh properties and improve durability.In practice, superplasticizers are used t